Use of cardiac biomarkers in neonatology

Proteomics and Biomarkers in Neonatology

SMARTT use of cardiac biomarkers.

Emergency physicians’ ongoing quest for the perfect biochemical marker is understandable, if quixotic. After all, we constantly balance the increasing pressures of emergency department (ED) overcrowding with the desire to provide optimum care to each patient. This dilemma is especially critical in the assessment of chest pain. Studies repeatedly show that 2%–6% of patients with acute myocardial...

Biomarkers in neonatology: the next generation of tests.

Over the past two decades, neonatal clinicians have commonly used host response biomarkers to diagnose and assess the severity of systemic infection. Most of these biomarkers, such as acute-phase proteins or cytokines, are non-specific immunomodulating mediators of the inflammatory cascade. With advances in biochemical/genetic research, it is anticipated that future biomarkers will be 'organ an...

cardiac biomarkers: a focus on cardiac regeneration

historically, biomarkers have been used in two major ways to maintain and improve better health status: first, for diagnostic purposes, and second, as specific targets to treat various diseases.   a new era in treatment and even cure for the some diseases using reprograming of somatic cells is about to be born. in this approach, scientists are successfully taking human skin cells (previously co...

Sertraline alters level of adenosine deaminase activity, oxidative stress markers and cardiac biomarkers (homocysteine cardiac troponin I) in rats

The aim of this study is whether oxidative stress markers, homocysteine (Hcy), cardiac troponin I (cTnI) and the activity of adenosine deaminase (ADA) alter following administration of different doses of sertraline. Sixty male Wistar rats were assigned into four groups. Sertraline at doses of 20, 40 and 80 mg / kg / day) were administered to three groups through gastric gavage for 90 days. The ...